T790M resistance mutations in EGFR+ lung cancer – EGFR Positive Lung Cancer UK

T790M resistance mutations in EGFR+ lung cancer – EGFR Positive Lung Cancer UK

EGFR Positive Lung Cancer UK shared on X:

“New research offers hope for those with T790M resistance mutations in EGFR+ lung cancer. Scientists have identified CDDO-Me, a compound that shows potential in preclinical studies to stop tumour growth.”

Machine learning-aided discovery of T790M-mutant EGFR inhibitor CDDO-Me effectively suppresses non-small cell lung cancer growth

Authors: Rui Zhou, Ziqian Liu, Tongtong Wu, Xianwei Pan, Tongtong Li, Kaiting Miao, Yuru Li, Xiaohui Hu, Haigang Wu, Andrew M. Hemmings, Beier Jiang, Zhenzhen Zhang, Ning Liu