The October edition of editors’ picks from the 10 AACR journals
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The October edition of editors’ picks from the 10 AACR journals

American Association for Cancer Research (AACR) shared a post on X:

“The October edition of editors’ picks from the 10 AACR journals features a head-to-head comparison of two CAR T therapies, a new type of blood test for colorectal cancer, and more. Learn more on the AACR Blog.”

1. “A Multicenter Real-life Prospective Study of Axicabtagene Ciloleucel versus Tisagenlecleucel Toxicity and Outcomes in Large B-cell Lymphomas”

Authors: Federico Stella, Annalisa Chiappella, Beatrice Casadei, Rosalba Miceli, Paolo Corradini et al.

2. “The History of Chromosomal Instability in Genome-Doubled Tumors”

Authors: Toby Baker, Siqi Lai, Andrew Lynch, Maxime Tarabichi, Peter Van Loo et al.

3. “Blood Magnesium Level and Risk of Hepatocellular Carcinoma in a Prospective Liver Cirrhosis Cohort”

Authors: Xinyuan Zhang, Longgang Zhao, Qi Dai, Tao Hou, Christopher Danford, Michelle Lai, Xuehong Zhang.

4. “Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells”

Authors: Vasyl Eisenberg, Shiran Hoogi, Erel Katzman, Ayal Hendel, Cyrille Cohen et al.

5. “Preventive Treatment with a CD73 Small Molecule Inhibitor Enhances Immune Surveillance in K-Ras Mutant Pancreatic Intraepithelial Neoplasia”

Authors: Lincoln Strickland, Wendao Liu, Usama Hussein, Jennifer Bailey-Lundberg et al.

6. “Multidimensional Fragmentomics Enables Early and Accurate Detection of Colorectal Cancer”

Authors: Yuepeng Cao, Nannan Wang, Xuxiaochen Wu, Jun Bao, Liu Yang et al.

7. “A Genomics-Driven Artificial Intelligence–Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms”

Authors: Fresia Pareja, Higinio Dopeso, Yi Kan Wang, Thomas Fuchs, Jorge Reis-Filho et al.

8. “First-Line Anlotinib Treatment for Soft-Tissue Sarcoma in Chemotherapy-Ineligible Patients: An Open-Label, Single-Arm, Phase 2 Clinical Trial”

Authors: Tao Li, Ying Dong, Yongzhong Wei, Zhaoming Ye, Binghao Li et al.

9. “Evaluating Debio 1347 in Patients with FGFR Fusion-Positive Advanced Solid Tumors from the FUZE Multicenter, Open-Label, Phase II Basket Trial”

Authors: Petros Grivas, Elena Garralda, Funda Meric-Bernstam, Anna Pokorska-Bocci, Keith Flaherty et al.

10. “NAPRT Silencing in FH-Deficient Renal Cell Carcinoma Confers Therapeutic Vulnerabilities via NAD+ Depletion”

Authors: Katelyn Noronha, Karlie Lucas, Sateja Paradkar, Juan Vasquez, Ranjit Bindra et al.

12. “FZ-AD005, a Novel DLL3-Targeted Antibody–Drug Conjugate with Topoisomerase I Inhibitor, Shows Potent Antitumor Activity in Preclinical Models”

Authors: Qingsong Guo, Bei Gao, Ruiwen Song, Wei Lu, Tong Yang et al.

13. “Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation”

Authors: Anna Rutkowska, Christian Eberl, Thilo Werner, Marcus Bantscheff, Giovanna Bergamini et al.

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